ABSTRACT
Selected short distance runners, middle distance runners and long distance runners were subjected to graded exercise on a treadmill. The maximum aerobic power (VO2 max) and other indices related to oxygen transport system viz. heart rate, ventilation volume, breathing reserve, dyspnoeic index, O2 pulse and RQ were recorded at respective VO2 max work loads, and the values were compared. Long distance runners and middle distance runners showed a significantly higher VO2 max than the short distance runners when VO2 max was expressed per unit of body weight. Among the endurance runners, long distance runners had a significantly lower resting pulse rate as well as the maximum heart rate during work than the middle distance runners. On comparison, Ventilation Volume, Breathing reserve, Dyspnoeic index, O2 pulse and RQ at VO2 max work loads do not differ significantly among different categories of runners.
Subject(s)
Adult , Cardiovascular Physiological Phenomena , Dyspnea/blood , Heart Rate/physiology , Humans , Male , Oxygen/blood , Oxygen Consumption/physiology , Physical Endurance/physiology , Physical Fitness/physiology , Respiratory Physiological Phenomena , Running/physiologyABSTRACT
Estradiol dipropionate (0.005 mg/kg) increased the monoamine oxidase levels in pituitary, median eminence and uterus of ovariectomized rats. Centchroman (3,4-trans-2, 2-dimethyl-3-phenyl-4-p-(-pyrrolidinethoxy)-phenyl-7 methoxy chroman, 1.25 mg/kg) decreased the enzyme levels in pituitary and median eminence but not in uterus. Centchroman, given to estradiol treated groups could not bring down the enhanced levels of the enzyme in the uterus.
Subject(s)
Animals , Benzopyrans/pharmacology , Centchroman/pharmacology , Estradiol/analogs & derivatives , Female , Hypothalamo-Hypophyseal System/drug effects , Median Eminence/drug effects , Monoamine Oxidase/metabolism , Pituitary Gland/drug effects , Rats , Uterus/drug effectsABSTRACT
Centchroman studied at various doses did not cause ovulation in immature rats as judged by morphological, histological and biochemical parameters whereas, 20 mg/kh dose caused early opening of vagina and cornification of the vaginal epithelial cells. However, no ovulation was detected by this regimen. No stimulatory effect was observed in the glycogen and cholesterol content in the ovaries of Centchroman treated rats. The effects on vagina persisted even in ovariectomised immature rats administered with Centchroman. The mode of various doses of Centchroman in immature rats as judged morphologically, histologically and biochemically has been discussed.